Learn about prescription IPF treatment

Learn More

The Costs of IPF

/

The costs of IPF

Caring for patients with IPF is expensive

Total medical costs for patients with IPF versus controls ($ per person-year)

IPF - $26,378
Control - $14,254

1. Collard HR et al. J Med Econ. 2012;15:829-835.

All medical costs are approximately twice as high for IPF as for those without IPF

Cost breakdown for patients with IPF versus those without 

1. Collard HR et al. J Med Econ. 2012;15:829-835.

Costs are predicted to increase as diagnosis of IPF increases

  • Increasing rates of diagnosis and higher rates of hospital admissions will likely increase the cost burden of IPF2,3
  • Increased number of bed days is associated with increased cost2
Bed days for patients with IPF have increased over time2

Adapted from Navaratnam V et al. Chest 2013

2. Navaratnam V et al. Chest. 2013;143:1078-1084.;
3. Lee AS et al. Respir Med. 2014;108:955-967.

Data on the burden of IPF on healthcare resource utilization are limited

A retrospective study evaluated the burden of illness associated with IPF, including healthcare resource utilization and costs, from records in United States claims databases over a 7.5-year period ending in September 20081
 

1. Collard HR et al. J Med Econ. 2012;15:829-835.
3. Lee AS et al. Respir Med. 2014;108:955-967.

Patients with IPF were more likely to be hospitalized than patients without IPF

  • In the 6 months prior to being diagnosed with IPF, more patients with IPF were hospitalized compared with those without IPF1:
   35% of patients with IPF
<10% of patients without IPF 

1. Collard HR et al. J Med Econ. 2012;15:829-835.

Patients with IPF were twice as likely to be admitted to the hospital

  • During the 1-year period following IPF diagnosis, all healthcare utilization was nearly two-fold higher in patients with IPF than in patients without IPF1
1. Collard HR et al. J Med Econ. 2012;15:829-835.

Patients with IPF underwent more testing than those without IPF

  • Most patients with IPF underwent pulmonary function testing and CT scanning during the study period1

1. Collard HR et al. J Med Econ. 2012;15:829-835.

Other studies have also evaluated cost of caring for patients with IPF

Wu and colleagues identified 1,735 patients who were diagnosed with IPF in a 6-year period (2006-2011) recorded in the PharMetrics Integrated Database (IMS Lifelink)4-6

4. Wu N et al. J Med Econ. 2015;18(4):249-257.
5. Wu N et al. Poster presented at the Pulmonary Fibrosis Foundation Summit. 2013. Available at http://www.pffsummit.org/assets/summit13-workbook-pro.pdf. Accessed July 12, 2017.
6. Yu Y et al. Presented at the American Thoracic Society Annual Meeting. San Diego, CA. 2014.

Healthcare utilization was higher for patients with IPF than for those without IPF

  • In the first year after diagnosis of IPF, patients consistently used more healthcare resources than matched controls in all areas studied4
Hospitalization
ER visits
Physician and pulmonologist visits

4. Wu N et al. J Med Econ. 2015;18(4):249-257.
 

Patients with IPF were frequently hospitalized in the first year

In the first year after diagnosis, patients withn IPF experienced5:

39% one or more all-cause hospitalizations
11% one or more IPF-related hospitalizations 
  5% one or more suspected AE-IPF leading to hospitalization 
 
72% at least one urgent outpatient exacerbation 

5. Wu N et al. Poster presented at the Pulmonary Fibrosis Foundation Summit. 2013. Available at http://www.pffsummit.org/assets/summit13-workbook-pro.pdf. Accessed July 12, 2017.

Hospitalizations for patients with IPF are expensive

~$14,000          All-cause hospitalizations       (avg: 9 days)
~$17,000          IPF-caused hospitalizations   (avg: 8 days)
~$15,000          Inpatient exacerbation            (avg: 6 days)
$444/incident    Urgent outpatient exacerbations

5. Wu N et al. Poster presented at the Pulmonary Fibrosis Foundation Summit. 2013. Available at http://www.pffsummit.org/assets/summit13-workbook-pro.pdf. Accessed July 12, 2017.
7. Yu Y et al. J Managed Care Spec Pharm 2016; 22(4):414-423.

Patients with IPF were more likely to use all healthcare services than non-IPF controls

*Values adjusted for different lengths of follow-up among IPF patients and non-IPF members. Adjustment based on generalized linear models controlling for patient demographics, comorbidities, and other relevant covariates.

4. Wu N et al. J Med Econ. 2015;18(4):249-257.

Summary

  • The direct medical costs for a patient with IPF are nearly two-fold greater than the costs for matched control patients1 
    • Hospital admission rates and outpatient visit rates are also nearly two-fold higher
  • The average cost of hospitalization ranges from $14,000 to $17,000 per event7 
    • The costs associated with acute exacerbation of IPF are also high, particularly if hospitalization is required
 
1. Collard HR et al. J Med Econ. 2012;15:829-835.
7. Yu Y et al. J Managed Care Spec Pharm. 2016; 22(4):414-423.

References

1. Collard HR et al. J Med Econ. 2012;15:829-835.
2. Navaratnam V et al. Chest. 2013;143:1078-1084.
3. Lee AS et al. Respir Med. 2014;108:955-967.
4. Wu N et al. J Med Econ. 2015;18(4):249-257.
5. Wu N et al. Poster presented at the Pulmonary Fibrosis Foundation Summit. 2013. Available at http://www.pffsummit.org/assets/summit13-workbook-pro.pdf. Accessed July 12, 2017.
6. Yu Y et al. Presented at the American Thoracic Society Annual Meeting. San Diego, CA. 2014.
7. Yu Y et al. J Managed Care Spec Pharm. 2016; 22(4):414-423.